I teach a range of tutorial topics on the Molecular and Cellular biochemistry course, 1st year- molecular cell biology, 2nd year, primer design and aspects of protein purification and 3rd year, extracellular matrix in health and disease. I lecture on the Biochemistry course to the 1st years and 3rd years. I host 4th year undergraduate students for their 18 week research projects.
I have been Tutor in Biochemistry at St Catherine’s since October 1998; before that I was a Royal Society University Research Fellow in the Sir William Dunn School of Pathology, University of Oxford. I was awarded the personal title of Professor in the 2004 Recognition of Distinction exercise at the University of Oxford.
My long term interest has been in understanding molecular mechanisms underlying human disease. My early work focussed on haemophilia B and Marfan syndrome. My main research interests currently are i) cell- extracellular matrix interactions in health and disease ( Marfan syndrome, acromelic dysplasias) and ii) cell surface organisation and regulation of the Notch receptor and its ligands ( Alagille syndrome). My work is currently funded by MRC, CRUK and Arthritis Research UK.
I have DPhil students and post-doctoral research assistants in my laboratory working on aspects of my research interests. I am college advisor to graduate students at St Catherine’s in the Medical sciences division.