I am Professor of Translational Psychiatry at the Department of Psychiatry and a consultant clinical psychiatrist. I was formerly a student at Catz from 1989-1992.

 

My overarching interest is in the role of genetic and environmental risk factors in the development of serious mental illness. In my work I employ a translational approach spanning human and laboratory studies. I am particularly interested in harnessing information from genomic studies to inform mechanistic understanding and biomarker and treatment development in serious mental illness. Current active projects include work on the role of altered calcium homeostasis in mental illness, and interdisciplinary studies of the effects of high-risk genomic copy number variants. I am co-chair of the NIHR. I previously held posts as Professor of Psychiatry in Edinburgh and Hodge Professor of Psychiatry in Cardiff. In addition to my research work I am also clinically active as a consultant in general adult and liaison psychiatry.