M Carmen Pinon

BSc, PhD Rio de Janeiro

Teaching

I teach Experimental Psychology and Neuroscience to Psychology and Biomedical Sciences students in the College.

About me

I have a first degree in Psychology and a PhD in Neuroscience.  I was the College Lecturer in Psychology at LMH from 2008 to 2011 and then College Lecturer at Queen's in 2013, in addition to being a College Lecturer at St Catz since 2012. I teach mainly first and second years in Neurophysiology, Cognitive and Behavioural Neuroscience and Perception.

Research

My initial Research interests were the study of the visual cortex and the anatomical basis for the Blindsight phenomena. For this purpose, I moved to Oxford in 2000 to work with Professor Alan Cowey at the Department of Experimental Psychology.  I then moved to the Department of Physiology, Anatomy and Genetics to work with Professor Zoltan Molnar on the development of the interactions between thalamus and cortex.  I am now interested in studying how Cognitive functions, more specifically decision making,  can be correlated with the driving situation and motor dysfunctions. For this aim, I started collaborations with Dr Mark Buckley at the Department of Experimental Psychology and Professor Helen Dawes from the Movement lab at Oxford Brookes University.

Main publications

1. Feedforward and feedback connections and their relation to the CytOx modules of V2 in Cebus monkeys Sheila Nascimento-Silva, Maria Carmen Pinõn Juliana G.M. Soares, Aglai P.B. Sousa and Ricardo Gattass Journal of Comparative Neurology, 2013, submitted.

2. Subplate and the Formation of the Earliest Cerebral Cortical Circuits, 2010. Zoltán Molnár, Wei Zhi Wang, Maria Carmen Piñon, Daniel Blakey, Shinichi Kondo, Franziska Oeschger, and Anna Hoerder-Saubedissen. Book Chapter in “New Aspects of Axonal Structure and Function”. Springer Science.

3.  Selective abnormalities in cortical layering and behavioral deficits in the cortex-specific Pax6cKO mice. Tuoc TC, Radyushkin K, Tonchev AB, Piñon MC, Ashery-Padan R, Molnár Z, Davidoff MS, Stoykova A. Journal of Neuroscience, July 1, 2009, 29(26):8335-8349. (Impact factor 8.238)

4.  Dynamic integration of subplate neurons into the cortical barrel field circuitry during postnatal development in the Golli-tau-eGFP (GTE) mouse. Maria Carmen Piñon, Ankeet Jethwa, Erin Jacobs, Anthony Campagnoni and Zoltán Molnár. Jounal of Physiology, April 2009, 587 (9). (Impact factor 4.881)

5.  Specificity and Plasticity of Thalamocortical Connections in Sema6A Mutant Mice Graham E Little, Guillermina López-Bendito, Annette E Rünker, Noelia García, Maria C Piñon, Alain Chédotal, Zoltán Molnár, Kevin J Mitchell. PLBio, April 2009, 28; 7 (4):e98. (Impact factor 14.7)

6.  Dissociation between molecular regionalization and area-specific cortical connectivity in the cortex specific Pax6 knock out mutant. Maria Carmen Piñon, Tran Cong Tuoc, Ruth-Ashery Padan, Zoltán Molnár and Anastassia Stoykova.    Journal Neuroscience, 28(35) 8724-8734. August 27, 2008. (Impact factor 8.238)

7.  David A Keays, Guoling Tian, Karine Poirier, Guo-Jen Huang, Christian Siebold, James Cleak, Peter Oliver, Martin Fray, Robert Harvey, Zoltan Molnar, Maria Carmen Piñon, Neil Dear, Steve D.M. Brown, Nicholas J Rawlins, Kay E Davies, Nick Cowan, Patrick Nolan, Jamel Chelly, Jonathan Flint. Mutations in α-tubulin cause hippocampal defects in mice and lissencephaly in humans. Cell  128, 45-57, Jan 12, 2007 (Impact factor 32.4)

8.    Genes involved in the formation of the earliest cortical circuits.  Zoltán Molnár, Anna Hoerder, Wei Zhi Wang, Jamin De Proto, Kay Davies, Sheena Lee, Ole Paulsen, Maria Carmen Piñon, Amanda F.P. Cheung  2007, Cortical Development: Genes and Genetic Abnormalities. Novartis Foundation      Symposium No. 288: 212-24; discussion 224-9, 276

 

 

 

 

College Lecturer in Psychology

Saul G Myerson

MB ChB Brist, MD Lond), MRCP, FESC

Teaching

I teach widely in clinical medicine, particularly general medicine and cardiology. Students from all three years of the clinical course at St. Catherine’s are taught, though focussing on year 6 in the first half of the year (pre-finals) and year 4 in the second half (year 5 are mostly out on specialist attachments). I also teach on the cardiology special study module in year 6. I lecture on cardiovascular physiology and imaging for both the University of Oxford and Brookes University, and oversee the training in cardiac imaging for cardiology registrars in Oxford, and training in the very specialised imaging of cardiac magnetic resonance. Outside Oxford, I lecture nationally and internationally on cardiology and cardiac imaging mostly.

About me

I’m a consultant cardiologist at the John Radcliffe Hospital in Oxford and an Honorary Senior Clinical Lecturer at the University of Oxford Department of Cardiovascular Medicine. I specialise in non-invasive cardiac imaging, particularly cardiovascular magnetic resonance, and my clinical and research interests are in valve disease and cardiomyopathies. I qualified from the University of Bristol and completed further training in London and Oxford. I have published widely, am editor of several Oxford Handbooks, including Cardiology Emergencies; Cardiovascular Magnetic Resonance; and Valve Disease, and was president of the British Junior Cardiologists Association from 2005-2007

Research

My research currently focusses on two main areas:

1) Quantitative measurement in cardiac valve disease, examining whether cardiovascular magnetic resonance (CMR), an advanced cardiac imaging technique, can improve the clinical management of patients with heart valve disease. The detailed quantitative information available from CMR may be able to predict the onset of symptoms in the 3 main types of cardiac valve disease (aortic stenosis, aortic regurgitation and mitral regurgitation). If successful, this research could have a major impact on the management of these patients, and help to elucidate the mechanisms of cardiac dysfunction in valve disease.

2) The physiological effects of ACE inhibitors in asymptomatic aortic stenosis. The potential for drug treatment of this common heart valve condition has being tested in an initial clinical trial, and I am setting up a second large multi-centre trial to examine the clinical benefit. Patients with aortic stenosis (a narrowing of the main valve out of the heart) can develop a thickened heart muscle and heart failure, both of which are detrimental. A group of drugs called ACE inhibitors may improve the ability of the heart muscle to cope with the valve disease, which might delay the onset of symptoms and the need for heart surgery. We hope to identify and improve the mechanisms underlying the progression to heart failure

Graduate supervision

I supervise DPhil students in the Department of Cardiovascular Medicine (currently 3), and my first student was awarded her DPhil last year.

Radcliffe Deparment of Medicine - Saul Myerson

 

 

College Lecturer in Medicine

Simon J Cassidy

MChem, DPhil Oxf
College Lecturer in Chemistry

Phillip Stansfeld

BSc Edin, PhD Leics

Teaching

I am a Stipendiary Lecturer in Biochemistry, covering aspects that include Structural Biology, Biophysical Techniques and Principles of Membrane Proteins.

About me

I have been a Post-Doctoral Research Associate in the Department of Biochemistry since 2007. I have been a Lecturer at St Catherine's since 2011.

Research

The general theme of my research is to use computational techniques to understand the properties of membrane proteins, which are involved in many diseases and are targets for approximately 50% of all pharmaceutical drugs.

I predominantly use molecular simulations to propose how these proteins move, engage with small molecules and interact with their lipid membrane environment.  I work in the Structural Bioinformatics and Computational Biochemistry (SBCB) Unit which is directed by Professor Mark S. P. Sansom and is based in the Biochemistry Department. My research is funded by the BBSRC.

Graduate supervision

I supervise a number of undergraduate and postgraduate students in the Department of Biochemistry.

College Lecturer in Biochemistry

Lucy J Hanington

BA, BM, BCh
College Lecturer in Medicine

Michael S Tombs

MA, DPhil
College Lecturer in Engineering Science

Letitia N M Jean

Lic, Maîtrise Paris-VI Pierre et Marie Curie, DEA, PhD Paris-XII Val-de-Marne
College Lecturer in Biological Sciences

Jesse C Petersen

BSc Western Australia, PhD Simon Fraser
College Lecturer in Physics

Ai Matsuno Fletcher

BEng, Keio, PhD Lond
College Lecturer in Chemistry

Claire Williams

BA Durh, MPhil, PhD Camb
College Lecturer in Portuguese
Associate Professor in Brazilian Literature and Culture

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