Structural analysis of human KDM5B guides histone demethylase inhibitor development.

Structural analysis of human KDM5B guides histone demethylase inhibitor development.

Professor Udo Oppermann

Johansson C, Velupillai S, Tumber A, Szykowska A, Hookway ES, Nowak RP, Strain-Damerell C, Gileadi C, Philpott M, Burgess-Brown N, Wu N, Kopec J, Nuzzi A, Steuber H, Egner U, Badock V, Munro S, LaThangue NB, Westaway S, Brown J, Athanasou N, Prinjha R, Brennan PE, Oppermann U. 'Structural analysis of human KDM5B guides histone demethylase inhibitor development.' (Nat Chem Biol. 2016)